ObjectiveFibroids are hormonally dependent uterine tumors. The literature on adiposity and fibroid prevalence is inconsistent. Previous work usually combined all those with a body mass index (BMI) ≥30 kg/m2 into a single category and relied…
Published associations between combined oral contraceptive use and uterine fibroid development have lacked prospective imaging with ultrasound to distinguish between incident and prevalent fibroids. The Study of Environment, Lifestyle, and …
OBJECTIVE: Female reproductive disorders (FRDs) are common health conditions that may present with significant symptoms. Diet and environment are potential areas for FRD interventions. We utilized a knowledge graph (KG) method to predict fa…
Research questionAre gravidity, parity and breastfeeding history associated with anti-Müllerian hormone concentration among African-American women of reproductive age?DesignThis study included baseline data from the Study of the Environment…
BackgroundMetals may influence reproductive health, but few studies have investigated correlates of metal body burden among reproductive-aged women outside of pregnancy. Furthermore, while there is evidence of racial disparities in exposure…
OBJECTIVE: Female reproductive disorders (FRDs) are common health conditions that may present with significant symptoms. Diet and environment are potential areas for FRD interventions. We utilized a knowledge graph (KG) method to predict fa…
BackgroundUterine fibroids are highly prevalent, benign tumors. They are the leading indication for hysterectomy, and Black women are disproportionally burdened. Soy-based infant formula contains phytoestrogens, and exposure during sensitiv…
OBJECTIVE: Fibroid treatments that have few side-effects and can preserve fertility are a clinical priority. We studied the association between serum vitamin D and uterine fibroid growth, incidence, and loss. DESIGN: A prospective community…
Scientists from multiple basic disciplines and an international group of physician-scientists from the field of obstetrics and gynecology presented recent studies and discussed new and evolving theories of uterine fibroid etiology, growth a…
BackgroundInjectable contraceptive use is common, with 74 million users worldwide. Use of the injectable contraceptive depot medroxyprogesterone acetate (DMPA) is associated with bone mineral density loss. We hypothesize that increased bone…
Study questionWhat proportion of fertilized human ova are lost before implantation?Summary answerAn estimated 40 to 50% of fertilized ova fail to implant.What is known alreadyPreimplantation loss is not detectable with current technology. P…
ObjectivesTo characterize reasons for hormonal contraceptive (HC) use in 1,455 African-American women, aged 23-35 years.Study designThe community-based cohort members were recruited from the Detroit, Michigan area in 2010-2012. HC history w…
BackgroundPhytoestrogen exposure from soy formula feeding during infancy may disrupt reproductive system development, resulting in altered menstrual bleeding in adulthood.MethodsWe investigated this relationship in a cohort of 1,696 young A…