Johnson L

INTRODUCTION: This case report reviewed a female client with numerous pre-existing conditions linked to gastrointestinal (GI) dysbiosis and systemic inflammation. Gastrointestinal ailments such as acid reflux/gastroesophageal reflux disease…

STUDY QUESTION: What is the recommended assessment and management of infertile women with polycystic ovary syndrome (PCOS), based on the best available evidence, clinical expertize and consumer preference? SUMMARY ANSWER: International evi…

BACKGROUND: In developed countries, primary health care increasingly involves the care of patients with multiple chronic conditions, referred to as multimorbidity. AIM: To describe the epidemiology of multimorbidity and relationships betwe…

The previously reported pyrrolidine class of progesterone receptor partial agonists demonstrated excellent potency but suffered from serious liabilities including hERG blockade and high volume of distribution in the rat. The basic pyrrolidi…