Rajan P. Adhikari

No ORCID on file · 1 paper in corpus · active 2024
2024
Engineered antibodies targeted to bacterial surface integrate effector functions with toxin neutralization to provide superior efficacy against bacterial infections
·doi:10.1101/2024.09.23.24313920

Anti-bacterial monoclonal antibody (mAb) therapies either rely on toxin neutralization or opsonophagocytic killing (OPK). Toxin neutralization protects the host from toxin-induced damage, while leaving the organism intact. OPK inducing anti…