Lyu Z

ORCID: 0000-0001-5833-1724 · 4 papers in corpus · active 2019-2024
2024
Risk-stratified CA125 screening integrating CA125 trajectories, trajectory-specific progression and transvaginal ultrasound for ovarian cancer.
Journal of ovarian research ·doi:10.1186/s13048-024-01535-9

BackgroundsCancer antigen 125 (CA125) is widely used for screening ovarian cancer (OC), yet its effectiveness remains debated. Potential factors may include ineffective cut-off value for CA125 in screening, as well as a lack of consideratio…

2021
Urinary equol levels are positively associated with urinary estradiol excretion in women.
Scientific reports ·doi:10.1038/s41598-021-98872-2

Isoflavones found in soy products are a promising class of nutrients that may have a positive effect on human health. In particular, the phytoestrogen metabolite equol is associated with a reduced risk of developing female hormone-related d…

2020
Mice lacking uterine enhancer of zeste homolog 2 have transcriptomic changes associated with uterine epithelial proliferation.
Physiological genomics ·doi:10.1152/physiolgenomics.00098.2019

Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase that suppresses gene expression. Previously, we developed a conditional null model where EZH2 is knocked out in uterus. Deletion of uterine EZH2 increased proliferation of lu…

2019
Knowledge Base Commons (KBCommons) v1.1: a universal framework for multi-omics data integration and biological discoveries.
BMC genomics ·doi:10.1186/s12864-019-6287-8

BackgroundKnowledge Base Commons (KBCommons) v1.1 is a universal and all-inclusive web-based framework providing generic functionalities for storing, sharing, analyzing, exploring, integrating and visualizing multiple organisms' genomics an…