Gui F

ORCID: 0000-0001-8329-7118 · 1 paper in corpus

2021

Pancreas-specific CHRM3 activation causes pancreatitis in mice.

JCI insight ·doi:10.1172/jci.insight.132585

Hyperstimulation of the cholecystokinin 1 receptor (CCK1R), a G protein-coupled receptor (GPCR), in pancreatic acinar cells is commonly used to induce pancreatitis in rodents. Human pancreatic acinar cells lack CCK1R but express cholinergic…