Marius Sieverding

ORCID: 0000-0002-2178-4743 · 1 paper in corpus

rct 2023

Substituting a randomised placebo control group with a historical placebo control in an endometriosis pain trial: a case study re-evaluating trial data using historical control data from another trial

BMJ open ·doi:10.1136/bmjopen-2022-063188

OBJECTIVE: The substitution of an in-study control population with a historical control (HC) population is considered a viable option for reducing the necessary recruitment of control patients. However, it is necessary to evaluate whether t…