Alan E Murphy

Anxiety is heritable and exists on a continuum, with symptoms ranging from adaptive threat response to clinical disorder. Here we performed a genome-wide association meta-analysis of generalized anxiety symptom severity in 693,869 individua…

We performed a genome-wide association meta-analysis of generalised anxiety symptom severity in 696,563 individuals of European ancestry from 14 cohorts. We identified 82 independent genome-wide significant variants within 76 loci, 41 of wh…

Advances in single-cell RNA-sequencing technology over the last decade have enabled exponential increases in throughput:   datasets with over a million cells are becoming commonplace.   The burgeoning scale of data generation, combined with…