IntroductionA transient window of uterine receptivity ensures that embryos implant in an optimal endometrial environment. Failure to establish or premature closure of the implantation window is thought to be a major cause of infertility, wh…
BackgroundEndoscopic gallbladder-preserving cholecystolithotomy (EGPC) has become an alternative option for treating cholecystolithiasis. However, developing a new method of EGPC in which the gallbladder wall is not damaged remains a challe…
BackgroundOvarian sex cord-stromal tumors (OSCSTs) are a rare and heterogeneous group of ovarian neoplasms, encompassing various subtypes such as ovarian thecoma, fibroma (including cellular fibroma), and ovarian granulosa cell tumors (OGCT…
As one of the three major malignant tumors in women, the morbidity of endometrial cancer is second only to that of cervical cancer and is increasing yearly. Its etiological mechanism is not clear, and the risk factors are numerous and commo…
Ovarian cancer is one of the most lethal gynecological malignancies and is often associated with fluid build-up in the peritoneal cavity, known as ascites. Nearly one-third of patients with ovarian cancer present with ascites at the time of…
Background and aimsLaparoscopic cholecystectomy (LC) often causes significant postoperative pain. While low-pressure pneumoperitoneum (8 mmHg) may reduce pain, optimal patient selection remains unclear. This trial compared pain outcomes bet…
Cuproptosis is a kind of programmed cell death in which copper reacts with the cycloaliphatic component of the tricarboxylic acid (TCA) cycle. In this study, we devised a predictive model and a theoretical framework to examine the variation…
BackgroundEpithelial ovarian cancer (EOC) currently lacks highly specific biomarkers for clinical screening. This study aimed to identify and validate novel auxiliary diagnostic markers for EOC.MethodsThrough integrated analysis of transcri…
IntroductionPrimary dysmenorrhea (PD) is characterized by pain during the menstrual cycle, affects women's health. Our group developed a traditional Chinese medicine plaster (Wentong plaster, WTT) for the treatment of PD. However, the under…
BACKGROUND: Successful implantation is dependent on a synchronous dialogue between several proteins that act to control cellular dynamics including actin and microtubule reorganisation and cell motility. An impaired crosstalk can lead to co…
Herlyn-Werner-Wunderlich syndrome (HWWS) combined with pelvic mesothelial cyst is a rare condition that can be easily misdiagnosed. Our center presents a case study of this disease to provide clinicians with valuable insights for accurate d…
AbstractBackgroundThe potential modifiable factors influencing irritable bowel syndrome (IBS) have not been thoroughly documented. We aimed to systematically investigate the modifiable factors associated with IBS, while accounting for the i…
Endometrial cysts of the ovary (EMC) may develop into endometriosis (EM)‑associated ovarian cancer over time (EAOC), but the pathogenesis of this disease has not been determined. In the present study, RNA sequencing was used to identify a f…
Nanodrug delivery systems (NDDS) have demonstrated broad application prospects in disease treatment, prevention, and diagnosis due to several advantages, including functionalization capability, high drug-loading capacity, drug stability pro…
BackgroundUlcerative colitis (UC) is an agnogenic chronic intestinal inflammatory disease. Umbilical cord-derived mesenchymal stem cell (UMSC) is a potential therapeutic approach against UC; however, the mechanisms underlying their efficacy…
ObjectiveSurgical site infections (SSI) after hysterectomy constitute significant postoperative complications, affecting patient recovery and healthcare costs. We conducted a systematic review of risk factors for SSI in patients undergoing …
Ovarian cancer remains a lethal disease marked by profound therapeutic resistance, largely orchestrated by a complex tumor microenvironment (TME) governed by metabolism-immune crosstalk. This review focuses on the spatiotemporal dynamics of…
Suicide is a complex behavior strongly associated with depression. Despite extensive research, an objective biomarker for evaluating suicide risk precisely and timely is still lacking. Using the precision resting-state fMRI method, we studi…
BackgroundThe relationship between negative emotions and chronic respiratory diseases remains largely unexplored. In this study, we employ Mendelian Randomization (MR) to investigate the potential causal relationship between negative emotio…
ObjectiveTo evaluate the efficacy of Fire Dragon Cupping (FDC) combined with Shaofu Zhuyu Decoction (SFZYD) in the treatment of primary dysmenorrhea (PD) with cold coagulation and blood stasis (CCBS).MethodologyA retrospective case-control …
BackgroundThe use of antioxidant-rich foods to treat female infertility has received significant attention in recent years. The aim of this study was to investigate the potential correlation between the composite dietary antioxidant index (…
BackgroundThe causal impact of lipid-lowering drugs on ovarian cancer (OC) and cervical cancer (CC) has received considerable attention, but its causal relationship is still a subject of debate. Hence, the objective of this study is to eval…
•The reference intervals calculated using RefineR, Kosmic, TMC, and non-parametric methods are similar.•TMC algorithm is more robust, demonstrates a high pass rate among the four methods and has the ability to automatically isolate outliers…