Gerome Breen

No ORCID on file · 6 papers in corpus · active 2013-2026

Study types

  • other 1

Condition tags

  • endometriosis 1
  • irritable_bowel_syndrome 1
2026
Genome-wide meta-analysis of quantitatively measured generalized anxiety symptoms in individuals of European ancestry
Nature human behaviour ·doi:10.1038/s41562-026-02476-7

Anxiety is heritable and exists on a continuum, with symptoms ranging from adaptive threat response to clinical disorder. Here we performed a genome-wide association meta-analysis of generalized anxiety symptom severity in 693,869 individua…

other 2025
Genome-wide insights into generalised anxiety using a dimensional symptom severity approach
medRxiv : the preprint server for health sciences ·doi:10.1101/2025.07.10.25331321

We performed a genome-wide association meta-analysis of generalised anxiety symptom severity in 696,563 individuals of European ancestry from 14 cohorts. We identified 82 independent genome-wide significant variants within 76 loci, 41 of wh…

2019
Genomic Influences on Self-Reported Childhood Maltreatment
·doi:10.1101/717314
2019
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Nature genetics ·doi:10.1038/s41588-019-0447-2

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

2018
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Nature genetics ·doi:10.1038/s41588-017-0011-x

Genome-wide association studies (GWAS) have identified >250 loci for body mass index (BMI), implicating pathways related to neuronal biology. Most GWAS loci represent clusters of common, noncoding variants from which pinpointing causal gene…

2013
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.
Nature genetics ·doi:10.1038/ng.2711

Most psychiatric disorders are moderately to highly heritable. The degree to which genetic variation is unique to individual disorders or shared across disorders is unclear. To examine shared genetic etiology, we use genome-wide genotype da…