Koutroulakis D

No ORCID on file · 1 paper in corpus

2012

Overexpression and ratio disruption of ΔNp63 and TAp63 isoform equilibrium in endometrial adenocarcinoma: correlation with obesity, menopause, and grade I/II tumors.

Journal of cancer research and clinical oncology ·doi:10.1007/s00432-012-1200-8

Purposep63 plays an important role in several intracellular processes such as transcription activation and apoptosis. p63 has two N-terminal isoforms, TAp63 and ΔNp63. TAp63 isoform has p53-like functions, while ΔNp63 acts as a dominant neg…