Krüger R

No ORCID on file · 2 papers in corpus · active 2013-2020
2020
Common diseases alter the physiological age-related blood microRNA profile.
Nature communications ·doi:10.1038/s41467-020-19665-1

Aging is a key risk factor for chronic diseases of the elderly. MicroRNAs regulate post-transcriptional gene silencing through base-pair binding on their target mRNAs. We identified nonlinear changes in age-related microRNAs by analyzing wh…

2013
Variants in CPA1 are strongly associated with early onset chronic pancreatitis.
Nature genetics ·doi:10.1038/ng.2730

Chronic pancreatitis is an inflammatory disorder of the pancreas. We analyzed CPA1, encoding carboxypeptidase A1, in subjects with nonalcoholic chronic pancreatitis (cases) and controls in a German discovery set and three replication sets. …