Xiao Han

ORCID: 0000-0002-8110-9977 · 4 papers in corpus
other 2025
The mitochondrial DNA copy number and ovary-related reproductive disorders: A bidirectional two-sample Mendelian randomization study
International Journal of Gynecology & Obstetrics ·doi:10.1002/ijgo.16057

OBJECTIVE: In the present study, a bidirectional two-sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA-CN) and ovary-related reproductive disorders (O…

2022
The role of artificial intelligence in accurate interpretation of HER2 IHC 0 and 1+ in breast cancers
·doi:10.21203/rs.3.rs-1967645/v1

Abstract The new HER2-targeting antibody drug conjugate offers the opportunity to treat patients with HER2-low breast cancer. Distinguishing HER2 immunohistochemistry (IHC) scores of 0 and 1+, is critical but also challenging due to HER2 h…

article 2018
Aquaporin-3 mediates ovarian steroid hormone-induced motility of endometrial epithelial cells
·doi:10.1093/humrep/dey290

STUDY QUESTION: How does aquaporin-3 (AQP3) affect endometrial receptivity? SUMMARY ANSWER: AQP3, which is regulated by the combination and estrogen (E2) and progesterone (P4), induces epithelial-mesenchymal transition (EMT) of endometrial …

2017
Dopamine D2 receptor signalling controls inflammation in acute pancreatitis via a PP2A-dependent Akt/NF-κB signalling pathway.
British journal of pharmacology ·doi:10.1111/bph.14057

Background and purposeDopamine has multiple anti-inflammatory effects, but its role and molecular mechanism in acute pancreatitis (AP) are unclear. We investigated the role of dopamine signalling in the inflammatory response in AP.Experimen…