PurposeTo identify candidate variants in genes possibly associated with premature ovarian insufficiency (POI).MethodsFourteen women, from 7 families, affected by idiopathic POI were included. Additionally, 98 oocyte donors of the same ethni…
Recent advances in molecular microbiology have enabled refined studies of the genital tract microbiota. This constitutes the basis of the present updated systematic review and meta-analysis which investigate vaginal dysbiosis (VD) as define…
BackgroundIn young women with poor ovarian response, luteal-phase ovarian stimulation (LPOS) is a potential method for collecting competent oocytes. The aim of this study was to assess the efficacy of LPOS compared with follicular phase ova…
Study questionDo mitochondrial DNA (mtDNA) copy number and heteroplasmy in human embryos affect the ongoing pregnancy rate?Summary answerOur study suggests that mtDNA copy number above a specific threshold is associated with the ongoing pre…