Stenzinger A

ORCID: 0000-0003-1001-103X · 2 papers in corpus

2023

Expanding the molecular spectrum of gene fusions in endometrial stromal sarcoma: Novel subunits of the chromatin remodeling complexes PRC2 and NuA4/TIP60 as alternative fusion partners.

Genes, chromosomes & cancer ·doi:10.1002/gcc.23109

Endometrial stromal sarcomas (ESS) are morphologically and molecularly heterogeneous. We report novel gene fusions (EPC1::EED, EPC1::EZH2, ING3::PHF1) identified by targeted RNA sequencing in five cases. The ING3::PHF1-fusion positive ESS p…

2020

Endometrial stromal sarcomas with BCOR-rearrangement harbor MDM2 amplifications.

The journal of pathology. Clinical research ·doi:10.1002/cjp2.165

Recently a novel subtype of endometrial stromal sarcoma (ESS) defined by recurrent genomic alterations involving BCOR has been described (HGESS-BCOR). We identified a case of HGESS-BCOR with a ZC3H7B-BCOR gene fusion, which harbored an ampl…