Falone S

ORCID: 0000-0002-5978-0545 · 2 papers in corpus

review 2018

Sirtuins in gamete biology and reproductive physiology: emerging roles and therapeutic potential in female and male infertility

Human Reproduction Update ·doi:10.1093/humupd/dmy003

BACKGROUND: Sirtuins (SIRT1-7) are a family of NAD+-dependent deacetylases that catalyze post-translational modifications of proteins. Together, they respond to metabolic challenges, inflammatory signals or hypoxic/oxidative stress, and are…

2015

Sirtuin Functions in Female Fertility: Possible Role in Oxidative Stress and Aging.

Oxidative medicine and cellular longevity ·doi:10.1155/2015/659687

In search for strategies aimed at preventing oxidative threat to female fertility, a possible role of sirtuins has emerged. Sirtuins (silent information regulator 2 (Sir2) proteins), NAD(+) dependent enzymes with deacetylase and/or mono-ADP…