Yuanyuan Lyu (5278652)

A. Enrichment plots for the top 4 biological functions enriched in the endometriosis group of the combined dataset. B-E. GSEA enrichment plots demonstrating the significant impact of endometriosis on the following pathways: IL1 and Megakary…

A. Box plots illustrating the differential enrichment of hallmark pathways between the high and low pyroptosis expression groups. B. Heatmap depicting the enrichment scores of hallmark pathways in the two groups. (PNG)

To investigate the differential enrichment of hallmark pathways between the high and low pyroptosis expression groups in endometriosis, GSVA was performed using the expression data of all genes in the combined dataset. The results of the GS…

A. Consensus clustering matrix for endometriosis samples, demonstrating the stability of the identified subtypes. B. Consistent Cumulative Distribution Function (CDF) plot for the consensus clustering analysis, indicating the optimal number…

A. Box plots comparing the abundance of immune cell subtypes identified by CIBERSORT between endometriosis and normal subgroups. B. Box plots comparing the ESTIMATE scores (Estimate Score, Immune Score, and Stromal Score) between endometrio…

Background Endometriosis (EMs) is a chronic inflammatory disease characterized by ectopic endometrial growth. This study aimed to identify and analyze potential signatures of pyroptosis-related genes in EMs. Methods We conducted a comprehe…