Jonathan L. Tilly
ORCID: 0000-0003-4712-8581
· 3 papers in corpus
Ovarian aging is characterized by a decline in both the total number and overall quality of oocytes, the latter of which has been experimentally tied to mitochondrial dysfunction. Clinical studies in the late 1990s demonstrated that transfe…
Three Specific Aims (SA) were proposed to test in mice if accelerated oocyte loss caused by Bclw deficiency or Bax gain-of-function drives ovarian surface mesothelial cell (OSMC) transformation: 1) characterize preneoplastic changes in OSMC…