Joachim Höchel

No ORCID on file · 4 papers in corpus · active 2017-2022

Study types

  • article 3
  • review 1

Condition tags

  • endometriosis 4
review 2022
Clinical pharmacokinetics ·doi:10.1007/s40262-021-01073-3

Vilaprisan is a highly potent selective progesterone receptor modulator in development for the treatment of symptomatic uterine fibroids and endometriosis. Its pharmacokinetics are characterized by rapid absorption, almost complete bioavail…

article 2019
Journal of clinical pharmacology ·doi:10.1002/jcph.1396

Intravaginal rings (IVRs) are an established option for continuous administration of drugs in women. The combination of anastrozole (ATZ) and levonorgestrel (LNG) in an IVR with an intended 4-week wearing period has been considered for long…

article 2018
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719118776806

BAY 1158061 is a potent monoclonal prolactin (PRL) receptor antibody, blocking PRL receptor (PRLR)-mediated signaling in a noncompetitive manner, which was tested in a randomized, placebo-controlled multiple dose study in postmenopausal wom…

article 2017
Journal of clinical pharmacology ·doi:10.1002/jcph.984

Abstract A study was performed to investigate the effect of an intravaginally administered antimycotic, an antibiotic, and a spermicide plus the co‐usage of tampons on the pharmacokinetics (PK) of levonorgestrel (LNG) and anastrozole (ATZ) …