Akemi Nishigaki

ORCID: 0000-0002-0153-7550 · 4 papers in corpus
review 2022
Reproductive medicine and biology ·doi:10.1002/rmb2.12428

BACKGROUND: Ovarian function is closely related to the degree of vascular network development surrounding the ovary. Maternal aging-related construction defects in this vascular network can cause ovarian hypoxia, which impedes oocyte nutrie…

lab-animal 2020
Heliyon ·doi:10.1016/j.heliyon.2020.e03985

AIM: The study aimed to elucidate the glycolytic metabolism of human endometrial stromal cells (hESCs) in hypoxic environment. MAIN METHODS: The hESCs were cultured in hypoxic environment, and their metabolic pathways were analyzed using m…

lab-animal 2016
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.3109/09513590.2015.1121225

Recent evidence points to a possible role for hypoxia-inducible factor (HIF)-1 in the pathogenesis and development of endometriosis. The objectives of this study were to investigate the critical role of HIF-1 in endometriosis and the effect…

observational 2012
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.3109/09513590.2012.736551

Stromal cell-derived factor-1 (SDF-1/CXCL12) and vascular endothelial growth factor (VEGF) are angiogenic factors that have possible roles in ovarian function. The objectives of this study were to investigate the association between the ind…