Polycystic ovary syndrome (PCOS) progression involves abnormal insulin signaling. SH2 domain-containing adaptor protein (Lnk) may be an important regulator of the insulin signaling pathway. We investigated whether Lnk was involved in insuli…
Cluster of differentiation 146 (CD146) is an endothelial cell adhesion molecule which is overexpressed in various types of malignant cancer, including ovarian cancer. However, whether CD146 is overexpressed in another two types of gynecolog…
BACKGROUND: Endometriosis is a common disease. The most widely used staging system of endometriosis is the revised American Fertility Society classification (r-AFS classification) which has limited predictive ability for pregnancy after sur…
ObjectiveTo explore the method of diagnosis for uterine septum and the clinical effect of hysteroscopic transcervical resection of the septum.MethodsOne-hundred ninety cases of patients with uterine septum who were diagnosed and treated at …
ObjectiveEmbryo implantation is directly affected by genes related to uterine receptivity. Studies have demonstrated the important roles of miRNAs in the regulation of gene expression. Our early miRNA chip analyses revealed that the mmu-miR…
ObjectiveAppropriate dosage of the long-acting depot gonadotrophin releasing hormone (GnRH) agonist has not been determined in long protocol for IVF, and one-third-dose depot triptorelin was compared with half-dose in a luteal long protocol…
BACKGROUND: To investigate the effect of pelvic floor Neuromuscular Electrical Stimulation (NMES) Therapy in improving endometrial thickness in women with thin endometrium. METHODS: 41 patients undergoing assisted reproduction with a thin e…
ObjectiveTo study the effect of telomerase activity (TA) in human luteinised granulosa cells (GCs) on the outcome of in vitro fertilisation treatment.MethodsFifty-six women, aged 23 to 39 years, were enrolled and divided into four groups ac…
Backgroundapogossypolone (ApoG2) is a novel derivate of gossypol. We previously have reported that ApoG2 is a promising compound that kills nasopharyngeal carcinoma (NPC) cells by inhibiting the antiapoptotic function of Bcl-2 proteins. How…
ObjectiveTo determine the inflammatory response in the peritoneal cavity by the presence of endometrial cells and the role of the mesothelium.DesignIn vivo study using mice.SettingUniversity research laboratory.Animal(s)Female Swiss Webster…