Grześkowiak E

ORCID: 0000-0002-9938-6729 · 1 paper in corpus

2024

Bidirectional pharmacokinetic drug interactions between olaparib and metformin.

Cancer chemotherapy and pharmacology ·doi:10.1007/s00280-023-04591-y

ObjectiveOlaparib is a PARP (poly-ADP-ribose polymerase) inhibitor used for maintenance therapy in BRCA-mutated cancers. Metformin is a first-choice drug used in the treatment of type 2 diabetes. Both drugs are commonly co-administered to o…