Federica Giangrazi

2026

Contribution of endometrial microbiome to inflammation-mediated infertility in women undergoing ART.

Human reproduction (Oxford, England) ·doi:10.1093/humrep/deaf252

Study questionIs the endometrial microbiome altered in women who fail to get pregnant after ART and do microbial-derived metabolites influence endometrial cellular mechanisms important for embryo implantation?Summary answerThe endometrial m…

other 2024

Evolutionary Analysis of the Mammalian IL-17 Cytokine Family Suggests Conserved Roles in Female Fertility

American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.13907

PROBLEM: The interleukin-17 (IL-17) family includes pro-inflammatory cytokines IL-17A-F with important roles in mucosal defence, barrier integrity and tissue regeneration. IL-17A can be dysregulated in fertility complications, including pre…

article 2021

P–305 The expression of innate immune factors in the eutopic endometrium of women with endometriosis

·doi:10.1093/humrep/deab130.304

Abstract Study question Is the expression of IL–17A and antimicrobial peptides (AMPs) altered in endometriosis? Summary answer IL–17A protein levels were similar in the endometrium of women with and without endometriosis but the expression …

2020

Dysregulation of the interleukin-17A pathway in endometrial tissue from women with unexplained infertility affects pregnancy outcome following assisted reproductive treatment.

Human reproduction (Oxford, England) ·doi:10.1093/humrep/deaa111

Study questionWhich transcriptomic alterations in mid-luteal endometrial scratch biopsies, taken prior to the assisted reproductive treatment (ART) treatment cycle are associated with unsuccessful pregnancy?Summary answerDysregulated interl…