Ahmed Z. Balboula

review 2024

Periostin's role in uterine leiomyoma development: a mini-review on the potential periostin poses as a pharmacological intervention for uterine leiomyoma

Archives of gynecology and obstetrics ·doi:10.1007/s00404-024-07435-z

Uterine leiomyomas, also known as fibroids or myomas, occur in an estimated 70-80% of reproductive aged women. Many experience debilitating symptoms including pelvic pain, abnormal uterine bleeding (AUB), dyspareunia, dysmenorrhea, and infe…

lab-animal 2022

A re-appraisal of mesenchymal-epithelial transition (MET) in endometrial epithelial remodeling

Cell and tissue research ·doi:10.1007/s00441-022-03711-z

Mesenchymal-epithelial transition (MET) is a mechanism of endometrial epithelial regeneration. It is also implicated in adenocarcinoma and endometriosis. Little is known about this process in normal uterine physiology. Previously, using pre…

lab-animal 2021

Capture and metabolomic analysis of the human endometrial epithelial organoid secretome

Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.2026804118

Suboptimal uterine fluid (UF) composition can lead to pregnancy loss and likely contributes to offspring susceptibility to chronic adult-onset disorders. However, our understanding of the biochemical composition and mechanisms underpinning …