Li R

RationaleSjögren syndrome (SS) is a systemic autoimmune disease with a variety of clinical presentations. Successful pregnancies and deliveries among these patients remain challenging. This manuscript describes a case report of diagnosis, d…

ObjectiveTo explore the clinical efficacy of transumbilical laparoendoscopic single-site extracorporeal surgery (TU-LESS-E) in the treatment of giant ovarian cysts and huge cystic pelvic masses.MethodologyThis was a retrospective study. Six…

BackgroundThe optimal surgical approach for hysterectomy in patients with complex large uteri remains controversial, particularly in those with uterine enlargement and obesity. This study aimed to compare perioperative outcomes and complica…

BackgroundCervical squamous cell carcinoma (CESC) constitutes a substantial global health burden, especially in resource-limited regions. The identification of reliable biomarkers is critical for developing a clinically applicable nomogram …

Endometriosis is a refractory estrogen-dependent gynecological disease in which ovarian endometriosis(OE) is the most common, and the main cell components are endometrial epithelial cells and stromal cells. However, constructing ectopic end…

BackgroundNatural cycle in vitro fertilization (NC-IVF) represents a convenient and safe assisted reproductive technology, making it particularly advantageous for patients with poor ovarian response (POR). This research evaluates the effect…

BackgroundOocyte vitrification, a widely utilized assisted reproductive technology for fertility preservation, can address emergencies arising from the unavailability of sperm from the male partner on the day of oocyte retrieval. However, t…

BACKGROUND: Endometriosis (EMs), characterized by ectopic endometrial growth causing infertility. Endoplasmic reticulum stress (ERS) is an important cellular defense mechanism. However, the correlation between ERS and EMs remains unclear. W…

OBJECTIVE: This study aims to develop a machine learning-based predictive model for patients with endometriosis, with the goal of precisely identifying key factors and reliable predictive markers that influence live birth outcomes following…

Ectopic pregnancy (EP) is a common yet fatal complication of in vitro fertilization-embryo transfer (IVF-ET) and intracytoplasmic sperm injection (ICSI). We aim to establish and validate a nomogram in patients undergoing double fresh cleava…

This study investigates changes in regional homogeneity (ReHo) of the brain in patients with adenomyosis accompanied by dysmenorrhea (AMD) before and after uterine artery embolization (UAE) surgery. ReHo is a resting-state functional magnet…

PurposeMaternal age-related fertility decline is considered to be directly attributed to either embryonic or endometrial factors. Aneuploidy, as the dominant defect in aging embryos, has long diverted attention away from the effects of endo…

BackgroundInfertility affects millions globally, with significant social, emotional, and economic consequences. While frozen-thawed embryo transfer (FET) is a cornerstone of assisted reproductive technology, its clinical pregnancy success r…

BACKGROUND: Epidermal cysts are benign subcutaneous masses resulting from the implantation of epithelial cells, following trauma or surgery. Giant spontaneous epidermal cysts of the labia minora are rare. To date, only 3 cases of epidermal …

BACKGROUND: endometriosis as a common gynecologic finding significantly affects the quality of life of many women. An accurate understanding of the epidemiological characteristics of endometriosis is essential for disease control and preven…

ObjectiveTo evaluate the effects of GnRH-a pretreatment with 1.5 mg or 3.75 mg, in combination with hormone replacement therapy (HRT), on pregnancy outcomes in women with polycystic ovary syndrome (PCOS) undergoing frozen embryo transfer (F…

The increased risk of infertility and endometrial lesions (such as endometrial hyperplasia or cancer) in polycystic ovary syndrome (PCOS) are closely associated with the lack of cyclical transformation in the endometrium. However, the under…

BACKGROUND: Adenomyosis is a prevalent gynecological condition among women of reproductive age and is commonly associated with heavy menstrual bleeding, severe dysmenorrhea, and infertility. These symptoms impose a substantial burden on bot…

ObjectiveTo study the correlation between anti-Müllerian hormone levels and pregnancy outcomes after in vitro fertilization/intracytoplasmic sperm injection in women with polycystic ovary syndrome, which remains controversial.MethodsThis re…

BackgroundThis retrospective study aimed to examine the influence of hormonal and metabolic parameters across varying body mass index (BMI) levels on embryo quality and pregnancy outcomes in fresh embryo transfer cycles using assisted repro…

ObjectiveTo evaluate the effect of prior uterine cavity procedures on clinical and neonatal outcomes in patients undergoing first-time in vitro fertilization-embryo transfer with donor sperm (IVF-ET with DS).MethodsThis retrospective cohort…

BackgroundEpithelial ovarian cancer (EOC) currently lacks highly specific biomarkers for clinical screening. This study aimed to identify and validate novel auxiliary diagnostic markers for EOC.MethodsThrough integrated analysis of transcri…

Endometriosis (EMS) is a chronic disease characterized by unclear etiology, influenced by various genetic and environmental factors, with no definitive biomarkers available for early screening. Recent studies suggest that the abdominal micr…