Zhaoyang Zhong

ORCID: 0000-0002-2338-038X · 3 papers in corpus · active 2025-2026

Study types

  • article 2
  • other 1

Condition tags

  • endometriosis 3
other 2026
Stromal cell-derived itaconate promotes endometriosis via macrophage NRF2 and lysosomal pH modulation
Redox biology ·doi:10.1016/j.redox.2026.104101

Endometriosis (EM) is driven by immune dysregulation and macrophage dysfunction, yet the underlying mechanisms remain unclear. Here, metabolomic profiling revealed excessive itaconate accumulation in EM lesions, primarily due to elevated ci…

article 2025
Iron overload-induced ferroptosis in CD8+ T cells leads to functional abnormalities that promote endometriosis progression
BMC medicine ·doi:10.1186/s12916-025-04369-4

BACKGROUND: Endometriosis (EM) exhibits localised iron overload. However, the contribution of ferroptosis to EM pathogenesis remains unclear. We investigated how iron overload affects CD8⁺ T cell immune function and the underlying ferroptot…

article 2025
Stromal cell–macrophage metabolic crosstalk via itaconate promotes immune imbalance in endometriosis
·doi:10.1016/j.jri.2025.104703