Messoud Ashina

No ORCID on file · 3 papers in corpus
review 2025
Hallmarks of primary headache: part 3 - cluster headache
The journal of headache and pain ·doi:10.1186/s10194-025-02145-6

BACKGROUND: Cluster headache (CH) is a rare primary headache disorder characterized by recurrent episodes of strictly unilateral excruciating pain accompanied by trigemino-autonomic signs, which significantly impacts the quality of life, so…

rct 2021
Efficacy and safety of fremanezumab in patients with episodic and chronic migraine with documented inadequate response to 2 to 4 classes of migraine preventive medications over 6 months of treatment in the phase 3b FOCUS study
The journal of headache and pain ·doi:10.1186/s10194-021-01279-7

BACKGROUND: Fremanezumab, a fully humanized monoclonal antibody (IgG2Δa) selectively targets the calcitonin gene-related peptide and has proven efficacy for the preventive treatment of migraine. In this study, we evaluated the long-term eff…

meta-analysis 2017
Calcitonin gene-related peptide and pain: a systematic review
The journal of headache and pain ·doi:10.1186/s10194-017-0741-2

BACKGROUND: Calcitonin gene-related peptide (CGRP) is widely distributed in nociceptive pathways in human peripheral and central nervous system and its receptors are also expressed in pain pathways. CGRP is involved in migraine pathophysiol…