Beata Seeber

Setting parameter for nuclei size. The nucleus size was determined as depicted in Fig. 4a. It was based on blue color detection (hematoxylin staining). Brown color expressed by cell was restricted from interior radius −4,81 μm to exterior r…

Manual counting of nerve fibers. Region of interests were selected randomly and marked with a border to obtain an area of 1Â mm2 each. A single nerve fiber was marked manually by using a tool available in HistoquestÂŽ software. (JPG 565Â kb…

BACKGROUND: The roles of the neurotrophins NGF (Neurotrophic growth factor) and BDNF (brain-derived neurotrophic factor) in neuronal growth and development are already known. Meanwhile, the neurotrophin receptors TrkA (tropomyosin related k…

BACKGROUND: High plasma concentrations of the vitamin E-binding protein afamin have been previously shown to be associated with insulin resistance and metabolic syndrome. We set out to determine whether the concentration of afamin in the se…

BACKGROUND: Comparative proteomics has recently identified afamin, the newest member of the albumin gene family, as a potential biomarker for ovarian cancer. The aim of this study was the analytical and clinical evaluation of a sandwich enz…

•We present the case of a premenopausal woman, who developed an endometriosis based endometrial carcinoma at the mons pubis.•After a three year follow-up period the patient remains disease free.

There is a great need for biomarkers that can serve as surrogates for important clinical endpoints such as endometriosis. The pursuit of a marker has been hampered by disparate study designs, small samples, and controversy regarding desired…

Einleitung: Unter der selten auftretenden extragenitalen Endometriose nimmt die pulmonale Form eine Sonderstellung ein. Bedingt durch die zyklusabhängigen Blutungen können Spontanpneumothoraces auftreten, die oft nicht in Zusammenhang mit E…

CONTEXT: Previous studies have implicated a deficiency in the inflammatory response in women who develop endometriosis. The specific immunological deficits have not been completely elucidated. OBJECTIVE: Our objective was to identify diffe…

Context Previous studies have implicated a deficiency in the inflammatory response in women who develop endometriosis. The specific immunological deficits have not been completely elucidated. Objective Our objective was to identify differen…

Context: Previous studies have implicated a deficiency in the inflammatory response in women who develop endometriosis. The specific immunological deficits have not been completely elucidated. Objective: Our objective was to identify differ…

OBJECTIVE: To identify potential novel biomarkers that differ between subjects with and without endometriosis and that might aid in developing a noninvasive, serum-based diagnostic test. DESIGN: Case-control evaluation of a diagnostic test…

The objective of this case-control study of 242 reproductive-age women was to determine the concentration of afamin in the serum and peritoneal fluid of women with and without endometriosis and to test afamin as a diagnostic marker of endom…

Fragestellung: Die Endometriose ist eine häufige Erkrankung während der reproduktiven Lebensphase der Frau, die mit chronischen Schmerzen und Subfertilität einhergeht. Ihre Diagnose beruht auf dem laparoskopischen und histologischen Nachwei…

OBJECTIVE: To evaluate whether a combination of putative markers of inflammation and CA-125 could serve as a multiple-marker screening test for endometriosis in a heterogeneous population of patients. DESIGN: Case-control evaluation of a d…

Because imaging methods are unreliable for diagnosing or staging endometriosis, a definitive diagnosis requires surgery. The fact that the disease produces a local, and probably also a systemic, inflammatory process raises the possibility t…