Wuest M

No ORCID on file · 2 papers in corpus · active 2014-2016
2016
Synthesis and pre-clinical evaluation of an (18)F-labeled single-chain antibody fragment for PET imaging of epithelial ovarian cancer.
American journal of nuclear medicine and molecular imaging

Anti-CA125 antibodies have been used in immunoassays to quantify levels of shed antigen in the serum of patients who are under surveillance for epithelial ovarian cancer (EOC). However, there is currently no molecular imaging probe in the c…

2014
Immuno-PET of epithelial ovarian cancer: harnessing the potential of CA125 for non-invasive imaging.
EJNMMI research ·doi:10.1186/s13550-014-0060-4

BackgroundEpithelial ovarian cancer (EOC) is characterized by the overexpression of cancer antigen 125 (CA125), a mucinous glycoprotein that serves as a tumor biomarker. Early diagnosis of EOC is plagued by its asymptomatic nature of progre…