Peter W. Nathanielsz

Age is the number one risk factor for breast cancer, yet the underlying mechanisms are unexplored. Age-associated mammary stem cell (MaSC) dysfunction is thought to play an important role in breast cancer carcinogenesis. Non-human primates …

Human and animal studies show that suboptimal intrauterine environments lead to fetal programming, predisposing offspring to disease in later life. Maternal obesity has been shown to program offspring for cardiovascular disease (CVD), diabe…

This study investigated whether the prostaglandin H synthase (PGHS) enzyme activity of sheep fetal placental cotyledon can be induced by cortisol at 128-131 days of gestation (dga) as compared to gestational age matched controls, before PGH…