Roya Rozati

Background: Endometriosis is a chronic, debilitating gynecological disorder characterized by the ectopic presence of endometrial-like tissue, often leading to pain and infertility. However, the role of mitochondrial dynamics, mitophagy, and…

Background: Endometriosis is a chronic, estrogen-dependent gynecological condition that is closely linked to infertility. Although significant progress has been made in assisted reproductive technologies (ART), including in vitro fertilizat…

Background: Endometriosis, a chronic gynecological condition affecting reproductive-age women, is strongly associated with infertility. Gonadotropin-releasing hormone agonists (GnRH-a) are widely used for endometriosis management and may im…

Background: Endometriosis is a chronic inflammatory condition where the precise cause of endometriosis is still not unclear. Mitochondrial dysfunction has been reported in severe forms of endometriosis. However, the role of mitochondrial dy…

Background: Endometriosis is a chronic inflammatory condition where the precise cause of endometriosis is still not unclear. Mitochondrial dysfunction has been reported in severe forms of endometriosis. However, the role of mitochondrial dy…

Endometriosis, being an estrogen-dependent condition, can lead to subfertility in women. Those facing difficulty achieving pregnancy goals may need assistance from assisted reproductive technology (ART). Due to the challenges posed by endom…

Objective: Estrogen and Progesterone hormones play a pivotal role in the pathogenesis of Endometriosis. In the present study, relative quantification of PR-A and PR-B expression in eutopic endometrial tissue and endometriotic implants was d…

Introduction: Endometriosis is a prevalent, benign, estrogen-dependent, chronic gynecological disorder associated with pelvic pain and infertility. Despite its prevalence and impact on reproductive health, the underlying molecular mechanism…

Objective: This study aims to determine the prevalence of endometriosis in women in South India, the epidemiological factors involved, and evaluate the symptomatic burden associated with it. Design: A large-scale Hospital-based study was co…

Endometriosis is a chronic benign gynecological disease characterized by the presence of ectopic endometrial tissue outside of the uterus cavity. Human Endometrium is a highly regenerative tissue. The aim of our study is to screen potential…

BACKGROUND: Toll-like receptor 2 (TLR2) and interferon-gamma (IFN-γ) coordinate with a diverse array of cellular programs through the transcriptional regulation of immunologically relevant genes and play an important role in immune system, …

BACKGROUND: Til date, none of the diagnostic techniques available for the detection of female genital tuberculosis (FGTB) are 100% accurate. We therefore, proposed to use the endometrial tissue biopsies (ETBs), ovarian tissue biopsies (OTBs…

The present study was designed to explore the association between the SNP +405G>C of the VEGF gene with the risk of endometriosis, and endometriosis associated with adenomyosis and chocolate cysts. Following extraction of genomic DNA, genot…

Background: Endometriosis is a female physical disorder that happens when cells from the lining of the womb (uterus) grow in other areas of the body i.e., outside of uterine cavity and leads to infertility. It represents a major personal a…

AIM: To investigate whether the interferon-gamma (IFNG) gene dinucleotide (CA)-repeat polymorphism is responsible in part for genetic susceptibility to endometriosis in South Indian women. METHODS: Following extraction of genomic DNA, geno…

BACKGROUND & OBJECTIVE: Endometriosis is one of the most commonly encountered benign problems in gynaecology. It is frequently associated with chronic pelvic pain, dysmenorrhoea, menorrhagia and dyspareunia, which lead to infertility. To de…

Background: Endometriosis is one of the most commonly encountered benign problems in gynaecology. It is frequently associated with chronic pelvic pain, dysmenorrhoea, menorrhagia and dyspareunia, which lead to infertility. We determined the…

Background To evaluate the possible association between phthalate esters (PEs) and the occurrence of endometriosis. Blood samples were collected from 99 infertile women with endometriosis (study group); 135 age-matched women without endomet…

OBJECTIVE: To evaluate the possible association between phthalate esters (PEs) and the occurrence of endometriosis. DESIGN: Case-control study. SETTING: Department of Reproductive Medicine, Bhagawan Mahavir Medical Research Centre, Matern…

The objective of this study was to detect the probable association between polychlorinated biphenyls (PCBs) and phthalate esters (PEs), and the occurrence of endometriosis in a prospective case control study. We found that PCBs and PEs may …