Patrícia Dias Fernandes

ORCID: 0000-0001-6870-6745 · 9 papers in corpus
article 2024
Peptides ·doi:10.1016/j.peptides.2024.171294

Endometriosis is a gynecological condition characterized by the growth of endometrium-like tissues outside of the uterine cavity. Currently available drugs are efficacious in treating endometriosis-related pain, however it's not a targeted …

article 2022
Pharmaceuticals (Basel, Switzerland) ·doi:10.3390/ph15111414

BACKGROUND: Current drugs for the treatment of endometriosis are not able to completely cure the condition, and significant side effects hinder the continuation of treatment. Therefore, it is necessary to search for new drug candidates. In …

preprint 2022
·doi:10.20944/preprints202210.0219.v1

Background: Current drug for the treatment of endometriosis is not able of completely cure and significant side effects hinder the continuation of treatment. So, the search for new drug candidates is necessary, and the use of plants extract…

review 2022
Molecules (Basel, Switzerland) ·doi:10.3390/molecules27134034

Endometriosis is a gynecological condition characterized by the growth of endometrium-like tissues inside and outside the pelvic cavity. The evolution of the disease can lead to infertility in addition to high treatment costs. Currently, av…

article 2019
·doi:10.1096/fasebj.2019.33.1_supplement.670.16

Endometriosis is a gynecological condition characterized by the growth of endometrium‐like tissues within and outside of the pelvic cavity. Currently available drugs are only efficacious in treating endometriosis‐related pain, however it's …

article 2017
·doi:10.1096/fasebj.31.1_supplement.1068.8

Tibouchina granulosa is an ornamental tree commonly found in Brazil and some species of the genus are used in popular medicine. Researches from our group have shown that the tea from the leaves present a significant wound healing effect and…

2016
PloS one ·doi:10.1371/journal.pone.0156271

LASSBio-1524 was designed as inhibitor of the IKK-β (kappa β kinase inhibitor) enzyme, which participates in the activation of the nuclear factor κB (NF-κB) canonical pathway, and its three N-acylhydrazone new analogues, LASSBio-1760, LASSB…

article 2015
The Journal of pharmacy and pharmacology ·doi:10.1111/jphp.12479

OBJECTIVES: The hormonal treatment for endometriosis frequently fails to completely eradicate endometriotic implants. A new therapeutic treatment is needed. This study investigates the in-vitro effect of Copaifera langsdorffii oil-resin on …

other 2010
Fertility and sterility ·doi:10.1016/j.fertnstert.2009.11.037

OBJECTIVE: To analyze the antiangiogenic effects of the selective cyclooxygenase-2 (COX-2) inhibitor parecoxib on the growth of endometrial implants in a rat model of peritoneal endometriosis. DESIGN: Pharmacologic interventions in an expe…