K J Sales

No ORCID on file · 4 papers in corpus
lab-animal 2010
Cellular signalling ·doi:10.1016/j.cellsig.2009.09.012

Prostaglandins exert their effects on target cells by coupling to specific G protein-coupled receptors (GPCRs) that are often co-expressed in the same cells and use alternate and in some cases opposing intracellular signaling pathways. This…

lab-animal 2008
Oncogene ·doi:10.1038/sj.onc.1210883

Cellular adhesion to extracellular matrix is a central phenomenon for the maintenance of tissue integrity and cellular movement. Collectively, these processes are regulated by a fine-tuned balance between the formation and loosening of adhe…

review 2004
Trends in endocrinology and metabolism: TEM ·doi:10.1016/j.tem.2004.08.006

Prostaglandins are bioactive lipids that exert an autocrine or paracrine function by binding to specific G-protein-coupled receptors (GPCRs) to activate intracellular signalling and gene transcription. Prostaglandins are key regulators of r…

review 2003
Reproduction (Cambridge, England) ·doi:10.1530/rep.0.1260559

Prostaglandins are bioactive lipids produced from arachidonic acid by cyclooxygenase (COX) enzymes and specific terminal prostanoid synthase enzymes. After biosynthesis, prostaglandins exert an autocrine-paracrine function by coupling to sp…