Kai-Lee Wang — Endo Lab

2021

Perspectives on the Role of Isoliquiritigenin in Cancer.

Cancers ·doi:10.3390/cancers13010115

Isoliquiritigenin (2',4',4-trihydroxychalcone, ISL), one of the most important bioactive compounds with a chalcone structure, is derived from licorice root. Licorice is commonly known as Glycyrrhiza, including Glycyrrhiza uralensis, Glycyrr…

2020

Salvia sclarea L. Essential Oil Extract and Its Antioxidative Phytochemical Sclareol Inhibit Oxytocin-Induced Uterine Hypercontraction Dysmenorrhea Model by Inhibiting the Ca2+-MLCK-MLC20 Signaling Cascade: An Ex Vivo and In Vivo Study.

Antioxidants (Basel, Switzerland) ·doi:10.3390/antiox9100991

Salvia sclarea essential oil is used as an aromatic therapy for dysmenorrhea. Sclareol-one of the natural products isolated from S. sclarea-displays anti-inflammatory and antioxidant activities; however, researchers have not yet evaluated t…

article 2018

Fucoidan Inhibits the Proliferation of Leiomyoma Cells and Decreases Extracellular Matrix-Associated Protein Expression

·doi:10.1159/000493660

BACKGROUND/AIMS: Uterine leiomyomas (ULs) are benign uterine tumors, and the most notable pathophysiologic feature of ULs is excessive accumulation of extracellular matrix (ECM). Fucoidan is a polysaccharide extracted from brown seaweeds th…