Chad Huff

No ORCID on file · 2 papers in corpus

observational 2022

Copy Number Variants Are Ovarian Cancer Risk Alleles at Known and Novel Risk Loci

Journal of the National Cancer Institute ·doi:10.1093/jnci/djac160

BACKGROUND: Known risk alleles for epithelial ovarian cancer (EOC) account for approximately 40% of the heritability for EOC. Copy number variants (CNVs) have not been investigated as EOC risk alleles in a large population cohort. METHODS:…

other 2022

Polygenic risk modeling for prediction of epithelial ovarian cancer risk

European journal of human genetics : EJHG ·doi:10.1038/s41431-021-00987-7

Polygenic risk scores (PRS) for epithelial ovarian cancer (EOC) have the potential to improve risk stratification. Joint estimation of Single Nucleotide Polymorphism (SNP) effects in models could improve predictive performance over standard…