Sam Mesiano

ORCID: 0000-0002-3981-5317 · 8 papers in corpus
2026
The Pathophysiology of Spontaneous Preterm Birth: Emerging Mechanisms Reviewed by the Preterm Birth International Collaborative.
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-026-02108-5

Around 10% of global births are preterm (before 37 weeks of gestation), posing a significant challenge to maternal and neonatal health. Preterm infants face an increased risk of mortality and long-term health complications, impacting their …

article 2024
ALTERED ENDOMETRIAL CELL PROGESTERONE RESPONSIVENESS IN THE ETIOLOGY OF ENDOMETRIOSIS
·doi:10.1016/j.fertnstert.2024.07.277
article 2015
Abundance and Localization of Progesterone Receptor Isoforms in Endometrium in Women With and Without Endometriosis and in Peritoneal and Ovarian Endometriotic Implants
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719115585145

BackgroundSeveral studies suggest that resistance to progesterone may contribute to the pathophysiology of endometriosis. Progesterone mediates its biological activity via the 2 progesterone receptor (PR) isoforms (PR-A and PR-B). Effects o…

review 2015
Role of nuclear progesterone receptor isoforms in uterine pathophysiology
Human Reproduction Update ·doi:10.1093/humupd/dmu056

BACKGROUND: Progesterone is a key hormonal regulator of the female reproductive system. It plays a major role to prepare the uterus for implantation and in the establishment and maintenance of pregnancy. Actions of progesterone on the uteri…

article 2013
Endometriosis, endometrium, implantation and fallopian tube
·doi:10.1093/humrep/det211

Study question: To compare the pregnancy rate in patients submitted to FET (Frozen Embryos Transfer) of cleavage stage embryos (Group 1), or at the blastocyst stage (Group 2). Summary answer: Our data showed that the transfer of frozen blas…

article 2013
Expression of progesterone receptor isoforms -a and -b in adenomyosis
·doi:10.1016/j.fertnstert.2013.07.698
article 2002
Progesterone Withdrawal and Estrogen Activation in Human Parturition Are Coordinated by Progesterone Receptor A Expression in the Myometrium
·doi:10.1210/jc.87.6.2924

In human parturition, progesterone withdrawal and estrogen activation are not mediated by changes in progesterone and estrogen levels. Instead, these events could be facilitated by changes in the responsiveness of the myometrium to progeste…

article 2002
Progesterone Withdrawal and Estrogen Activation in Human Parturition Are Coordinated by Progesterone Receptor A Expression in the Myometrium
·doi:10.1210/jcem.87.6.8609

In human parturition, progesterone withdrawal and estrogen activation are not mediated by changes in progesterone and estrogen levels. Instead, these events could be facilitated by changes in the responsiveness of the myometrium to progeste…