Endometriosis is a common finding among women with infertility, and women who are diagnosed with endometriosis are almost twice as likely to experience infertility. Mechanisms by which endometriosis causes infertility remain poorly understo…
BACKGROUND: There is no agreed consensus on the optimal surgical treatment for pain associated with endometriosis. OBJECTIVES: To compare improvement in symptoms and quality-of-life in patients undergoing excisional endometriosis surgery (…
INTRODUCTION: There is uncertainty about the advantages and disadvantages of laparoscopic hysterectomy compared with abdominal hysterectomy, particularly the relative rate of complications of the two procedures. While uptake of laparoscopic…
Evidence-based data for endometriosis management are limited. Experiments are excluded without adequate animal models. Data are limited to symptomatic women and occasional observations. Hormonal medical therapy cannot be blinded if recognis…
Evidence-based data for endometriosis management are limited. Experiments are excluded without adequate animal models. Data are limited to symptomatic women and occasional observations. Hormonal medical therapy cannot be blinded if recognis…
Objective The aim of this study was to assess inter-rater reliability for components of the Visual-Numeric Endometriosis Scoring System (VNESS). VNESS is a novel system for describing surgical findings in each compartment of the pelvis in a…
STUDY QUESTION: What outcomes should be reported in all studies investigating uterus-sparing interventions for treating uterine adenomyosis? SUMMARY ANSWER: We identified 24 specific and 26 generic core outcomes in nine domains. WHAT IS K…
Transabdominal cerclage (TAC) is a recognised treatment for recurrent spontaneous late miscarriage or preterm birth due to cervical weakness. This can be performed via an open procedure before and during pregnancy, or a laparoscopic techniq…
BACKGROUND: The COVID-19 pandemic has had a significant effect on healthcare services, particularly affecting patients who suffer from chronic conditions. However, the pandemic's effect on endometriosis surgery is not yet known. OBJECTIVES…
Ovaries are frequent sites for endometriosis, and endometriomas constitute an important subtype of this condition due to their easy detectability and their impact on fertility and fertility treatment. While all treatment options for endomet…
STUDY OBJECTIVE: To retrospectively evaluate the ability of routinely collected preoperative ultrasound data to predict bowel resection during surgery for rectovaginal endometriosis. DESIGN AND SETTING: Patients at the University College L…
Background and Objective: Adenomyosis is a benign disorder of the uterus characterised by infiltration of endometrial glands and stroma into the myometrium. It is present in a significant proportion of women presenting with heavy menstrual b…
BACKGROUND: Adenomyosis is a common benign gynaecological condition that has been associated with heavy and/or painful periods, subfertility and poor obstetric outcomes including miscarriage and preterm delivery. Studies evaluating treatmen…
INTRODUCTION: Adenomyosis can adversely reduce chances of pregnancy in couples undergoing assisted conception. We aim to evaluate the effect of two different downregulation protocols on the reproductive outcomes in women with moderate and s…
Objective: To describe the optimum approach to surgery in young women. Background: Endometriosis is frequently diagnosed in young women who present with pelvic pain, particularly when it is resistant to medical therapies and surgery is freq…
Fertility preservation for women with ovarian endometriosis: it is time to adopt it as routine practice
Objective: To determine the impact of the COVID-19 pandemic on surgery for severe endometriosis in the UK at a national, regional and centre-level. Design: Population-based national cohort study. Population: All women undergoing endometrios…
OBJECTIVE: To assess the prevalence and morphological appearance of deep endometriosis and ovarian endometrioma using pelvic ultrasound examination in women attending for an early pregnancy assessment. METHODS: This was a prospective obser…
Advances in preoperative diagnostics as well as in surgical techniques for the treatment of endometriosis, especially for deep endometriosis, call for a classification system, that includes all aspects of the disease such as peritoneal endo…
BACKGROUND: Endometriosis is a common benign gynaecological disease that affects pelvic structures and causes adhesions. Endometriosis outside the pelvis exists but is rarer. Deep endometriosis may affect organs such as the urinary bladder,…