Jiang W

ORCID: 0000-0003-0576-7545 · 60 papers in corpus
review 2018
Molecular medicine reports ·doi:10.3892/mmr.2018.9142

Histone modifications are the key epigenetic mechanisms that have been identified to regulate gene expression in many human diseases. However, in the early developmental stages, such as in utero and the postnatal stages, histone modificatio…

review 2018
The Journal of international medical research ·doi:10.1177/0300060518776769

Objective An increasing trend of uterine rupture (UR) after laparoscopic surgery of the uterus (LSU) has been observed. Although the overall incidence is extremely low, UR may have catastrophic outcomes. Therefore, investigation of its pote…

lab-animal 2018
BMC cancer ·doi:10.1186/s12885-018-4918-0

BACKGROUND: The tumour microenvironment conferred by mesenchymal stem cells (MSCs) plays a key role in tumour development and progression. We previously determined that platelet-activating factor receptor (PAFR) was overexpressed in ovarian…

review 2018
Frontiers in immunology ·doi:10.3389/fimmu.2018.01188

Toll-like receptor (TLR) 4 is expressed on normal and malignant prostate epithelial cells. The TLR4 and its downstream signaling pathways mediate innate immune responses in the host against invading pathogens. However, multiple lines of evi…

observational 2017
BMC anesthesiology ·doi:10.1186/s12871-017-0394-3

BACKGROUND: Chronic post-surgical pain (CPSP) after hysterectomy has been recognized as a major clinical problem in the Western World. Reports on post-hysterectomy pain are relatively scarce in China. The aim of the current study was to pro…

lab-animal 2014
International journal of clinical and experimental pathology

OBJECTIVE: Mouse bone marrow mesenchymal stem cells (BMSCs) have been demonstrated to differentiate into female endometrial epithelial cells (EECs) in vivo. Our previous studies demonstrated that BMSCs can differentiate in the direction of …

other 2013
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc ·doi:10.1038/modpathol.2013.51

Endometriosis involving the mucosa of the intestines is rare, but may lead to diagnostic pitfalls. We reviewed 15 cases (seven biopsies and eight resections) from 14 patients. The patients' mean age is 48 years (31-66 years). Presenting sym…

lab-animal 2012
Journal of ovarian research ·doi:10.1186/1757-2215-5-21

BACKGROUND: Ovarian cancer is predominant of epithelial cell origin and often present at an advanced stage with poor prognosis. Most animal models of ovarian carcinoma yield thecal/granulose cell tumors, rather than adenocarcinomas. The bes…

lab-animal 2012
Journal of medicinal chemistry ·doi:10.1021/jm300930n

Human cytochrome P450 aromatase catalyzes with high specificity the synthesis of estrogens from androgens. Aromatase inhibitors (AIs) such as exemestane, 6-methylideneandrosta-1,4-diene-3,17-dione, are preeminent drugs for the treatment of …

lab-animal 2011
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2011.10.012

OBJECTIVE: To investigate the differentiation conditions of bone marrow mesenchymal stem cells (BMSCs) into endometrial epithelial cells and to confirm the effect of 17β-estradiol in this process. STUDY DESIGN: BMSCs were cultured alone or…