Tasuku Hirayama

Iron (Fe) and heme are essential for numerous biological processes, but their dysregulation contributes to cancer, neurodegeneration, and ferroptosis. This review summarizes the development and applications of N-oxide chemistry-based fluore…

Intracellular labile iron is an iron species which is not or weakly bound to proteins and depicts an important effect on homeostatic regulation in cells. An excess or deficiency of iron can cause oxidative damage to key cellular biomolecule…

Ovarian endometriosis is a recognized risk for infertility and epithelial ovarian cancer, presumably due to iron overload resulting from repeated hemorrhage. To find a clue for early detection and prevention of ovarian endometriosis-associa…