J L Wittliff

No ORCID on file · 4 papers in corpus
observational 1986
Clinical physiology and biochemistry

Estrogen receptor (ER) and progestin receptor (PR) levels and their respective dissociation constants (Kd) were determined by titration assay and Scatchard analyses in 319 human uteri. Levels of receptors were neither age nor uterine weight…

other 1985
American journal of obstetrics and gynecology ·doi:10.1016/0002-9378(85)90471-5

Variations in cytochrome P-450 levels may influence the responsiveness of uterine and breast tissue as well as carcinomas to endocrine therapy and may be of particular importance with agents such as tamoxifen (Nolvadex) where hydroxylation …

lab-animal 1985
Surgery, gynecology & obstetrics

A study using a Sprague-Dawley rat model was designed to correlate morphologic and intracellular steroid receptor alteration with danazol therapy. One uterine horn was removed for cytoplasmic estrogen receptor analysis following four to eig…

lab-animal 1983
American journal of obstetrics and gynecology ·doi:10.1016/s0002-9378(16)32226-8

Sprague-Dawley rats with estrous cycles were exposed to danazol (Danocrine) at a single dose of 10 mg/kg for either 6 or 24 hours, or daily until a pattern of no cycles (6 days) was noted on vaginal smears. The animals were individually hou…