O P Luzardo — Endo Lab

lab-animal 2000

Photoaffinity labeling identification of a specific binding protein for the anabolic steroids stanozolol and danazol: an oligomeric protein regulated by age, pituitary hormones, and ethinyl estradiol

Endocrinology ·doi:10.1210/endo.141.9.7667

We have demonstrated previously that both rat and human liver microsomes contain a highly specific binding protein for the anabolic steroids stanozolol (ST) and danazol (DA). In this study we solubilized the male rat liver ST-binding protei…

lab-animal 1996

Identification of a specific binding site for the anabolic steroid stanozolol in male rat liver microsomes

The Journal of pharmacology and experimental therapeutics ·doi:10.1016/s0022-3565(25)21269-1

Male rat liver microsomes contain a [3H]dexamethasone binding site, capable of binding glucocorticoids and progesterone. We have shown previously that the 17 alpha-alkylated androgen, stanozolol, can inhibit the [3H]dexamethasone binding to…

lab-animal 1995

[3H]dexamethasone binding activity in liver microsomes is modulated differently by 17 alpha-alkylated androgens and testosterone in vivo

Pharmacology & toxicology ·doi:10.1111/j.1600-0773.1995.tb01025.x

Rat liver microsomes contain a single class of steroid binding sites, capable of binding various glucocorticoids and progesterone. In a previous article, we have described the in vitro interaction of several androgens with this binding site…