Stelios Michalas

No ORCID on file · 2 papers in corpus · active 2003-2006

Study types

  • article 2

Condition tags

  • endometriosis 2
  • endometrioma 1
article 2006
Insulin‐Like Growth Factor–1 Isoform mRNA Expression in Women with Endometriosis
Annals of the New York Academy of Sciences ·doi:10.1196/annals.1365.042

Pathogenesis of endometriosis involves growth factors, which are synthesized locally. Insulin-like growth factor-1 (IGF-1) prevents apoptosis and has mitogenic action on endometrial cells. The IGF-1 gene undergoes alternative splicing and r…

article 2003
Urokinase‐Type Plasminogen Activator and Insulin‐Like Growth Factor‐Binding Protein 3 mRNA Expression in Endometriotic Lesions and Eutopic Endometrium
Annals of the New York Academy of Sciences ·doi:10.1196/annals.1290.025

The peritoneal fluid of women with endometriosis contains an increased insulin-like growth factor 1 (IGF-1) bioavailability, which is produced by limited hydrolysis of urokinase-type plasminogen activator (uPA) on IGF-binding protein 3 (IGF…