Wang H

OBJECTIVE: To explore the mechanism of inhibitory effect of SLW on estrogen production by endometrial cells of endometriosis. METHOD: After the model of eutopic primary cultured endometrial cells of endometiosis and hysteromyoma in vitro w…

Immunophilin FKBP52 serves as a cochaperone to govern normal progesterone (P(4)) receptor (PR) function. Using Fkbp52(-/-) mice, we show intriguing aspects of uterine P(4)/PR signaling during pregnancy. Implantation failure is the major phe…

OBJECTIVE: To investigate the expressions of matrix metalloproteinase -2, -3 (MMP-2,-3) and tissue inhibitor of metalloproteinase-2 (TIMP-2) in internal uterine endometriosis tissue and endometrium from women with and without endometriosis …

Uterine decidualization, a key event for successful implantation, is critically controlled by stromal cell proliferation and differentiation. One hallmark event of decidualization is the acquisition of stromal cell polyploidy through termin…

OBJECTIVE: To identify the possible risk factors of endometriosis in Chengdu. METHODS: A hospital-based pair matched case-control study was carried out in 100 pair of female patients with endometriosis and their controls. The data were ana…

OBJECTIVE: To study the relationship between alteration of peritoneal lymphocyte transformation activity, its interleukin-2 (IL-2) release and infertility associated with endometriosis. METHODS: Peritoneal fluid was collected from 15 infer…

The incidence, mortality and survival of breast cancer patients from 1970 to 1993 were studied using data from the Cancer Registry of Norway. The age-adjusted incidence rate increased from 62.0 to 76.9 per 100,000 person-years during the pe…

A subset of human papillomaviruses (HPVs) is associated with the majority of cervical cancers; however, cofactors appear to be required for carcinogenic progression of HPV-induced neoplasia. As human herpesvirus-6 (HHV-6) was recently shown…