Qing Chen

ORCID: 0000-0002-1276-1064 · 9 papers in corpus
case-report 2024
Frontiers in medicine ·doi:10.3389/fmed.2024.1308299

This report described three cases with long-term severe dysmenorrhea, and these cases were referred to our department for medical help. The diagnosis of accessory cavitated uterine malformation (ACUM) was considered based on symptoms and ul…

lab-animal 2024
Cancer Immunology, Immunotherapy ·doi:10.1007/s00262-023-03596-z

BACKGROUND: Cervical cancer is a common malignant tumor in the female. Interleukin (IL)-17A is a proinflammatory factor and exerts a vital function in inflammatory diseases and cancers. M2 macrophage has been confirmed to promote tumor deve…

observational 2024
Medical science monitor : international medical journal of experimental and clinical research ·doi:10.12659/msm.943170

BACKGROUND Tumor-infiltrating immune cells (TIICs) are implicated in the survival of ovarian cancer (OVCA) patients, but their prognostic significance in advanced or metastatic OVCA patients treated with neoadjuvant chemotherapy (NCAT) has …

lab-animal 2023
Frontiers in genetics ·doi:10.3389/fgene.2023.1338411

Follicular atresia occurs in every stage of ovarian development, which is relevant to female fertility. In the past decade, increasing studies have confirmed that miRNAs, a class of short non-coding RNAs, play an important role in follicula…

observational 2023
Annals of clinical microbiology and antimicrobials ·doi:10.1186/s12941-023-00556-4

BACKGROUND: Chronic endometritis (CE) is a disease of continuous and subtle inflammation occurring in the endometrial stromal area, which is often asymptomatic or present with non-specific clinical symptoms. METHODS: This study investigate…

review 2021
Biology of sex differences ·doi:10.1186/s13293-021-00364-5

Sensory perception and emotional disorders are disproportionally represented in men and women and are thus thought to be modulated by different sex hormones in various conditions. Among the most important hormones perceived to affect sensor…

other 2015
PloS one ·doi:10.1371/journal.pone.0146159

Intrauterine adhesions (IUA) are a significant cause of menstrual disturbance and infertility, but their pathogenesis still remains unclear. Here, we investigated the expression of TGF-β and CCN2 in IUA endometrial tissue by immunohistochem…

meta-analysis 2014
PloS one ·doi:10.1371/journal.pone.0106761

Endometriosis is one of the most frequent benign gynecological disorders. Numerous studies have shown an association between GSTM1 and/or GSTT1 polymorphisms and endometriosis susceptibility. However, these associations remain inconclusive.…

lab-animal 2010
Human Reproduction ·doi:10.1093/humrep/deq287

BACKGROUND: p38 mitogen-activated protein kinase (p38 MAPK), a regulator of inflammation, may play a role in the pathogenesis of endometriosis (EM). We studied the effect of SB203580, a p38 MAPK inhibitor, on the development of EM in a mous…