Liwei Wang — Endo Lab

preprint 2023

Hydroxysafflor Yellow A ameliorates adenomyosis by improving IDH1-autophagy-EMT

·doi:10.22541/au.168966930.03401710/v1

Background and Purpose: Adenomyosis causes pain, abnormal bleeding, and infertility. Epithelial-mesenchymal transition (EMT) plays a critical role in the pathogenesis of adenomyosis. Current therapies are mainly hormone-dependent and their …

preprint 2020

T-cadherin deficiency promotes endometriosis progression through the PI3K/AKT/mTOR signaling pathway

·doi:10.21203/rs.3.rs-18041/v1

Abstract Background: Endometriosis is a progressive and benign disease characterized by the presence of endometrial glands and stroma tissue outside of the uterine cavity. Though endometriosis is a benign disease, it has the characteristics…

article 2019

T-cadherin inhibits invasion and migration of endometrial stromal cells in endometriosis

Human Reproduction ·doi:10.1093/humrep/dez252

STUDY QUESTION: What is the expression level of T-cadherin in endometriosis, and does T-cadherin play a role in regulating invasion and migration of endometrial stromal cells? SUMMARY ANSWER: T-cadherin expression was reduced in ectopic end…

article 2016

Overexpression of chloride channel-3 is associated with the increased migration and invasion ability of ectopic endometrial cells from patients with endometriosis

Human Reproduction ·doi:10.1093/humrep/dew034

STUDY QUESTION: Is chloride channel-3 (ClC-3) involved in regulating the biological behavior of endometrial stromal cells (ESCs)? SUMMARY ANSWER: ClC-3 promotes endometriotic cell migration and invasion. WHAT IS KNOWN ALREADY: ClC-3 plays a…