Hoekstra M

ORCID: 0000-0001-7463-2893 · 1 paper in corpus

2023

PRMT5 inhibition induces pro-inflammatory macrophage polarization and increased hepatic triglyceride levels without affecting atherosclerosis in mice.

Journal of cellular and molecular medicine ·doi:10.1111/jcmm.17676

Protein arginine methyltransferase 5 (PRMT5) controls inflammation and metabolism through modulation of histone methylation and gene transcription. Given the important role of inflammation and metabolism in atherosclerotic cardiovascular di…