Rita Trozzi

ORCID: 0000-0001-6556-5203 · 5 papers in corpus
preprint 2026
Spatially Resolved Epithelial–Immune Heterogeneity Identifies an Endometriosis Subtype with Molecular Features of Endometriosis-Associated Ovarian Cancer
·doi:10.21203/rs.3.rs-10497180/v1

Abstract Evidence suggests that clear cell and endometrioid ovarian carcinoma may arise from endometriosis. We previously identified that some endometriosis lesions exhibit a “cancer-like” PD-1/PD-L1 positive staining similar to endometr…

article 2025
Abstract PR018: Spatially resolved epithelial and immune heterogeneity reveals distinct endometriosis-related precursors to ovarian cancer
·doi:10.1158/1538-7445.ovarian25-pr018

Abstract Evidence suggests that certain histotypes of ovarian carcinoma -mainly clear cell (CCOC) and endometrioid (EOC) carcinoma-may arise from endometriosis (EAOC), although the biological mechanisms underlying this phenomenon remain unc…

article 2024
Abstract 3647: Digital spatial transcriptomic reveals different epithelial and immune cells signatures across endometriosis-related diseases: From simple ovarian endometriosis to ovarian cancer
·doi:10.1158/1538-7445.am2024-3647

Abstract Endometriosis represents a pressing medical concern, imposing a relevant burden on patients including potential malignant transformation into endometriosis-associated ovarian cancer (EAOC). Despite the process of cancer development…

article 2022
Impact of nerve‐sparing posterolateral parametrial excision for deep infiltrating endometriosis on postoperative bowel, urinary, and sexual function
International Journal of Gynecology & Obstetrics ·doi:10.1002/ijgo.14089

OBJECTIVE: To evaluate the functional outcomes of nerve-sparing surgery for deep infiltrating endometriosis (DIE) with or without posterolateral parametrectomy. METHODS: A multicenter, observational, retrospective, cohort study was performe…

2022
The impact of hysterectomy on oncological outcomes in postmenopausal patients with borderline ovarian tumors: A multicenter retrospective study.
Frontiers in oncology ·doi:10.3389/fonc.2022.1009341

Data about the oncological outcomes in women with borderline ovarian tumor (BOT) undergoing uterine-sparing surgery without ovarian preservation are poor. We aimed to assess the oncological outcomes in women with BOT undergoing uterine-spar…