Pisegna JR

ORCID: 0000-0002-4343-0989 · 2 papers in corpus

2019

Generalized Cytokine Increase in the Setting of a Multisystem Clinical Disorder and Carcinoid Syndrome Associated with a Novel NLRP12 Variant.

Digestive diseases and sciences ·doi:10.1007/s10620-019-05525-6

BackgroundNucleotide-binding oligomerization domain (NOD)-like receptors (NLRs) are a group of cytoplasmic sensors that survey danger signals released by invading pathogens or damaged tissue. Mutations in the NLRP subfamily affect pro-infla…

2016

A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation.

American journal of physiology. Gastrointestinal and liver physiology ·doi:10.1152/ajpgi.00212.2016

High-throughput technologies revealed new categories of genes, including the long noncoding RNAs (lncRNAs), involved in the pathogenesis of human disease; however, the role of lncRNAs in the ulcerative colitis (UC) has not been evaluated. G…