Kazuhiko Higuchi

ORCID: 0000-0003-1538-1291 · 1 paper in corpus

article 1993

Induction of true precocious puberty by neonatal treatment with danazol in female rats

·doi:10.1016/0304-3940(93)90636-y

Female rats at 5 days of age were given a single subcutaneous injection of varying doses of danazol or vehicle. Rats treated with 300 micrograms of danazol showed significant (P < 0.01, respectively) advancement in the day of vaginal openin…