Jianquan Xu

ORCID: 0000-0002-3441-2359 · 1 paper in corpus
2022
The amyloid precursor protein modulates the position and length of the axon initial segment offering a new perspective on Alzheimer’s disease genetics
·doi:10.1101/2022.01.23.477413

The small Aβ peptide has been hypothesized to be the main driver of Alzheimer’s disease (AD). Aβ is a proteolytic cleavage product of a larger protein, the amyloid precursor protein (APP), whose normal functions remain largely unexplored. W…