Hui Lei

ORCID: 0009-0002-1290-5061 · 3 papers in corpus
lab-animal 2024
Increased levels of villus-derived exosomal miR-29a-3p in normal pregnancy than uRPL patients suppresses decidual NK cell production of interferon-γ and exerts a therapeutic effect in abortion-prone mice
Cell communication and signaling : CCS ·doi:10.1186/s12964-024-01610-0

OBJECTIVE: Recurrent pregnancy loss (RPL) patients have higher absolute numbers of decidual natural killer (dNK) cells with elevated intracellular IFN-γ levels leading to a pro-inflammatory cytokine milieu, which contributes to RPL pathogen…

lab-animal 2024
MiR-135a-5p regulates window of implantation by suppressing pinopodes development and decidualization of endometrial stromal cells
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-024-03088-8

PURPOSE: The window of implantation (WOI) is a brief period during which the endometrium is receptive to embryo implantation. This study investigated the relationship between miR-135a-5p and endometrial receptivity. METHODS: Peripheral blo…

lab-animal 2024
TSG6-Exo@CS/GP Attenuates Endometrium Fibrosis by Inhibiting Macrophage Activation in a Murine IUA Model
Advanced materials (Deerfield Beach, Fla.) ·doi:10.1002/adma.202308921

Intrauterine adhesion (IUA) is characterized by the formation of fibrous scar tissue within the uterine cavity, which significantly impacts female reproductive health and even leads to infertility. Unfortunately, severe cases of IUA current…